Dose

n.

Heard in Cork, Waterford, Offaly, Galway and Limerick

An immense nuisance, annoyance, or a thoroughly aggravating situation.

In use

Me car wouldn't start in the lashing rain, what a bleeding dose!

Posh English

My motor car refused to ignite amidst the cascading rain, what an absolute vexation!

Same phrase, other counties